Stereo Core Biopsy This is a procedure for a small, hard to feel lump, mass or calcifications. While the breast is compressed, a nick is made in the skin after local anesthetic is administered. A needle is then inserted into the breast and is positioned so that the tip of the needle is centered at the site of the mass or calcifications. Mammographic x-ray views are taken to assure the correct location of the needle. Once in position, the biopsy part of the needle is activated and a sharp click is heard. The needle is then withdrawn. This part of the procedure may be repeated a number of times in order to obtain an adequate amount of tissue to send to the pathologist.